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ADAM/Benjamin
Cummings InterActive
Physiology® 9-System Suite

Item Name: InterActive Physiology®
9-System Suite CD-ROM
Item Number: PIM/D2001
Price: $495.95
Call 1-800-745-4557 to order by phone.
InterActive Physiology® significantly
enriches the teaching environment by providing
audio/visual understanding of complex topics. For
use as both a presentation and teaching tool in the
classroom,
as well as a study tool for students. This CD-ROM
covers nine body systems and features full-color
animations, sound, interactive quizzes, games, and
clinical scenarios that thoroughly demonstrate
difficult physiology concepts and help bridge the
gap between simply memorizing a concept and truly
understanding it
The Interactive Physiology
Institutional Edition contains the following all on
one CD-ROM:

Click on the link below to read details about the
topics included in that module: Cardiovascular
System, Muscular
System, Respiratory
System, Nervous
System, Urinary
System, Fluids
& Electrolytes, Nervous
II, Endocrine
and Digestive
System.
Interactive
Physiology Features:
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Anatomy
Each Body System begins with an
"Anatomy Review," giving students
a chance to brush up on the necessary
anatomy that will be covered in the body
system.
Animations
Animations show physiological
processes in action. They can be paused,
stepped through, or repeated to make it
easier to comprehend processes that change
over time, to correlate multiple events, or
to relate physiological functions with
graphical representations. Animations
concentrate on cellular and molecular
processes.
Self-Quizzes
Self-quizzes test and reinforce students'
understanding of concepts with interactive
exercises that encourage critical thinking
and problem solving. Engaging animations
allow students to predict outcomes and test
their understanding. Students can return to
the topic for a quick review with the click
of a link button.
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Textbook
Correlations
Students can access the appropriate chapter
outline from Human Anatomy and Physiology,
Third Edition, by Elaine N. Marieb, R.N.,
Ph.D. to help correlate the module topics
with the relevant pages and figures in the
textbook.
Learning
Goals
Every topic contains learning goals for the
student and a brief list of what the learner
should know before proceeding.
Virtual
Professor
Additional clarification and emphasis on
important, difficult concepts are provided
by Elaine Marieb, who appears on-screen as
the "Virtual Professor."
On-Screen
Glossaries
Important terminology presented in
"hot" form, so that users can
access on-screen glossaries and additional
information.
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Cardiovascular
System
Anatomy Review: The Heart. By illustrating
the external and internal heart from four different
views,
this topic provides students with greater
understanding of the spatial relationships among
heart structures. The overall circulation in the
body is animated.
Intrinsic
Conduction System. An animation shows the
pathway of depolarization in the heart, and ECG
waves are explained. The two are then put together
to help students understand the correlation between
an ECG graph and events in the heart. The quiz
includes matching and puzzle exercises, and then
students must apply their knowledge to two clinical
situations–a left bundle branch block and
tachycardia.
Cardiac Action
Potential. Using animations, this topic leads
students step-by-step through the difficult concepts
of pacemaker potentials and action potentials.
Animated events in autorhythmic and contractile
cardiac cells are correlated with animated graphs of
membrane potential. The quiz questions require
students to demonstrate their understanding of
membrane potential and the roles of various ion
channels.
Cardiac Cycle.
An animation of blood flow through the heart is
presented, followed by step-by-step animations and
explanations of the phases of the cardiac cycle. The
blood flow animation is then correlated with
animated graphs of pressure, ventricular volume, and
an ECG. This allows students to make the connections
between the graphs and events occurring in the
heart. The quiz tests student understanding of the
stages of the cardiac cycle in relation to heart
valves, blood flow, and the ECG/pressure/volume
graphs.
Cardiac Output.
Cardiac output is demonstrated in a way that could
only be done on computer! Students are also asked to
predict the effects of 10 different factors on heart
rate, stroke volume, and cardiac output, and then
give an explanation for each factor. In the quiz,
students must calculate cardiac output and relate it
to the volume of soda bottles, and demonstrate their
understanding of heart rate and stroke volume
regulation.
Blood Vessel
Physiology: Anatomy Review. Blood Vessel
Structure: The flow of blood is traced through the
blood vessels of the body, using animations to
demonstrate the structural and functional
characteristics of each vessel type.
Measuring Blood
Pressure. This topic illustrates what is
happening in the body when blood pressure is
measured. The quiz gives students an opportunity to
try their hand at interpreting blood pressure
measurement sounds.
Factors That
Affect Blood Pressure. Animations and analogies
are used to demonstrate the factors that affect
blood pressure. In the quiz, students must identify
the factors that will lower someone's blood
pressure.
Blood Pressure
Regulation. Using animations, this topic helps
students understand the complexities of short-term
and long-term regulation of blood pressure. In the
quiz, students can experiment with the effects of
nerve stimulation, epinephrine, and acetylcholine.
Also, they must correctly identify the chain of
events that begins when dehydration occurs, and when
blood volume and blood pressure are increased or
decreased.
Autoregulation and
Capillary Dynamics. In this topic, animations
and analogies are used to explain the control of
blood flow through individual organs (autoregulation)
and the movement of solutes and fluids across
capillary walls. In the quiz, students must apply
their knowledge of autoregulation to muscle cells.
Also, they must use their understanding of capillary
dynamics to predict how digested foods and
respiratory gases are transported across capillary
walls.
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Digestive System
Anatomy
Review: Overall Function of the GI System.
Discusses the four-layered wall of the GI tract (mucuosa,
submucosa, muscularis externa, and serosa).
Illustrates the anatomical features of the GI tract
and outlines their functions. The quiz questions ask
the student to identify and label structures,
complete a summary chart, match structures and
functions, and apply their understanding to a
clinical problem (acid reflux).
Control
of the Digestive System.
Step-by-step
illustration of the phases of control of the
digestive process. Discusses the involvement of the
parasympathetic, sympathetic, and enteric nervous
systems. Demonstrates the functions of
neurotransmitters and hormones in the digestive
process. In the quiz, students must demonstrate
their understanding of reflex activities of the GI
tract and apply what they've learned about
neurotransmitters to clinical problems (treatment of
diarrhea and dysentery).
Motility.
Describes the actions of the muscles of the GI tract
that mix and propel its contents. Animations
demonstrate peristalsis, segmentation, migrating
motility complexes, mass movements, defecation, and
vomiting. The quiz questions require students to
build a table identifying motility in the different
regions of the GI tract, create a chain of events
describing defecation, and apply their understanding
of motility to clinical problems (constipation and
diarrhea).
Secretion.
Illustrates GI tract secretions (salivary, gastric,
pancreatic, liver, and intestinal) and their
functions. Students travel through each region to
learn about neural and hormonal regulation of the
secretions. The quiz includes drag-and-drop
activities to identify specific secretions, and an
interactive activity to provide patient education to
someone who has had a gallbladder removed.
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Endocrine
System
Endocrine System Review.
Identifies the major endocrine glands and tissues,
the hormones they produce, their target tissues, and
a simple function for each hormone.
Biochemistry, Secretion, and Transport of Hormones. Covers
the chemical classes and solubility properties of
hormones, how hormones are synthesized, and the
stimuli that control hormone secretion.
The Actions of Hormones on Target Cells. Reviews
hormone receptors, second messenger systems and
transcription factors, insulin (including a
discussion of diabetes mellitus), and how hormones
induce changes in cellular metabolism.
The Hypothalamic-Pituitary Axis. An overview of
the anatomy of the hypothalamic-pituitary axis, a
review of its endocrine and neural control, a study
of the hypophyseal portal system, and a review of
thyroid hormone (including the causes and
consequences of hypo- and hypersecretion of TH and a
discussion of Graves' disease).
Response to Stress. A discussion of stress in
terms of endocrine function, the nervous system's
role in responses to stress, and a review of
epinephrine and cortisol (including a discussion of
Cushing's disease and Addison's disease).
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Fluids
and Electrolytes
Introduction to Body
Fluids. Describes the roles and movements of
fluids in the body, the composition of body fluids,
three fluid compartments, the roles and
compartmentalization of electrolytes, and osmosis.
Water Homeostasis.
Show how water enters and leaves the body, and what
happens when water homeostasis is disturbed.
Describes the mechanisms of water balance and how
they work to maintain water homeostasis.
Electrolyte
Homeostasis. Compares the exchange of water and
electrolytes between each of the fluid compartments
and discusses edema. Show how the body regulates
sodium, potassium, and calcium homeostasis.
Acid/Base
Homeostasis. Reviews principles of acids, bases,
pH, and dynamic equilibrium. Describes how the body
regulates pH through respiratory and renal controls.
Show respiratory and renal acidosis and alkalosis,
with clinical examples.
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Muscular
System
Anatomy Review:
Skeletal Muscle Tissue. Compares the three types of
muscle cells (skeletal, cardiac, and smooth).
Illustrates the levels of organization of skeletal
muscle tissue from a whole muscle down to the
subcellular level. The quiz questions ask the
student to complete a summary chart, label a muscle
cell, match definitions and structures, and put
together a puzzle.
The Neuromuscular
Junction. Shows the anatomy of a neuromuscular
junction and then illustrates, step-by-step, the
events that occur at the neuromuscular junction. A
summary animation puts all the steps together. In
the quiz, students must demonstrate their knowledge
of neuromuscular junction activity and apply what
they've learned to new situations with clinical
applications (the effects of curare, neostigmine,
and nicotine).
Sliding Filament
Theory. Describes the molecules that participate
in contraction, followed by an animation of how a
muscle cell contracts. The individual steps of the
sliding filament theory are then explained, and then
the full animation is shown again. The quiz
questions require students to put the events of a
cross bridge cycle in order and apply their
knowledge to explain rigor mortis.
Muscle Metabolism.
Illustrates the roles of ATP in a muscle cell and
describes how ATP is synthesized, using both
traditional flowcharts and in a more fanciful ATP
"factory." Students are asked to predict
the metabolic variations in different types of
muscle fibers. The highlight of the quiz is Muscle
Metabolism Mania, in which students can take turns
answering questions and earning points.
Contraction of
Motor Units. Animations show motor units of
different sizes in action. Also, students must
predict what will happen if a nerve to a muscle is
cut, and then test their hypothesis by
"cutting" the nerve to see the result. The
quiz uses arcade-style games and a basketball game
to relate motor unit size to real-life situations.
Contraction of
Whole Muscle. After introducing the concepts
related to muscle stimuli, this topic provides a lab
simulation allowing the user to increase the voltage
to an isolated muscle and then see the muscle's
response, a graph of the response, and an
explanation. Other simulations are given throughout
this topic, which could be used as a supplement or
substitute for a lab requiring the use of frog leg
muscles. In the quiz, cellular concepts are applied
to real-life situations.
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Nervous
System I.
Anatomy Review.
Describes features of neurons, the polarization of
neurons and the direction of information flow in the
cells. The quiz tests students' understanding of the
anatomy of neurons and relation of neuronal
structure to function.
Voltage Gated Ion
Channels. Continues the anatomy of neurons, but
at the channel level. The broad categories of
channels, their regional location, and unique
functions are described. The quiz tests students'
understanding of the channel types and their
functions.
Membrane
Potential. Develops the principles for
understanding how and why ions cross cell membranes.
Students study passive channels and the chemical and
electrical forces on Na+ and K+. The quiz tests
students' understanding of the features of passive
ion channels and the forces acting to move Na+ and
K+.
Action Potential.
Describes the permeability changes which bring about
the action potential at the ion channel level.
Students study the operation of voltage-gated
channels, and the ionic movements that result as
these channels open and close. Study of the
generation of the action potential is followed by
study of propagation of the action potential along
the axon. The quiz tests students' understanding of
the operation of voltage-gated channels, and
resulting sequential movement of Na+ and K+ across
the neuronal membrane.
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Nervous
System II.
Anatomy Review:
Synapsis. This topic begins by describing and
illustrating the properties and purpose of synapses.
Students observe how neuronal stimulation from the
somatic and autonomic nervous systems affect
different types of muscles. The actions of
inhibition and excitation are demonstrated. Students
learn the features of different types of synapses,
and electrical and chemical synapses are described.
The topic concludes by illustrating the presynaptic
and postsynaptic components of the chemical synapse.
Chemically Gated
Ion Channels. Provides an overview and
demonstration of the properties of passive and
active ion channels. Explains and illustrates the
principles of directly-acting neurotransmitters, and
students learn which ions are involved in generating
rapid excitatory or inhibitory postsynaptic
potentials. Goes on to explain how neurotransmitters
can act indirectly on ion channels via second
messengers to produce slow excitatory or inhibitory
postsynaptic potentials.
Synaptic
Transmission. Illustrates synaptic transmission
and outcome step by step, illustrating
neurotransmitter release, diffusion, binding, and
termination. Students learn that the effect of a
neurotransmitter depends upon receptor type, and
they see how Ach affects nicotonic and muscarinic
receptors in the central and autonomic nervous
systems. The excitatory effect of glutamate, and the
inhibitory effects of GABA and glycine, are
demonstrated. Illustrations of different behaviors
demonstrate the outcomes of directly-acting and
indirectly-acting neurotransmitters on synaptic
activity.
Synaptic
Potentials and Cellular Integration. This topic
begins by reviewing the properties of the action
potential. The differences in characteristics
between action potentials and synaptic potentials
are demonstrated by graphing their impulses. The
summation of synaptic potentials is explained, and
examples of temporal and spatial summation are
illustrated. The effect of combining inhibitory and
excitatory postynaptic potentials is demonstrated,
and the topic concludes with an explanation and
behavioral example of cellular integration.
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Respiratory
System
Anatomy
Review: Respiratory Structures. Using an
overview diagram, the flow of air is traced from the
external nares to the lungs. A Baboon analogy
demonstrates the relationship between the visceral
and parietal pleurae. Detailed art follows the flow
of air from the bronchial tree all the way to the
alveolus. Animations illustrate the types of cells
in the alveolus, showing alveolar macrophages in
action! The quizzes include labeling exercises and a
clinical question about pulmonary edema.
Pulmonary
Ventilation. This topic first demonstrates the
relationship between volume and pressure. The
movements of the thoracic cavity are correlated with
graphs and gauges showing pressure changes in the
lungs. Students are asked to predict the effect of
pneumothorax on the lungs. The topic discusses
airway resistance, and uses a baboon analogy to show
lung compliance. In the quiz, students must sequence
the events of inspiration and expiration, reinflate
a lung, as well as correlate pressure graphs with
airflow.
Gas Exchange.
After introducing gas laws, this topic explains the
factors affecting gas exchange in the lungs and
tissues. Also, animations illustrate the effect of
gas levels on the bronchioles and arterioles. In the
quiz, students must correctly identify gas values in
the lungs and tissues, and apply their knowledge of
gas laws and gas exchange to make predictions.
Gas Transport.
This topic discusses the different forms to which
oxygen and carbon dioxide are carried in the body.
The important oxygen-hemoglobin dissociation curve
is presented in a dynamic manner, and has a
predictable question to test understanding. The
animations enliven the chemistry, making the
molecules more than mere symbols. The quiz tests
student knowledge with challenging labeling and
sorting exercises, as well as predictable questions.
Control of
Respiration. This topic illustrates the
underlying importance of homeostasis in the control
of respiration. Through flowcharts, the topic walks
students through the feedback loop that controls
respiration. The topic discusses the effects of
hyper- and hypoventilation. The quiz tests
understanding of these concepts by asking students
to make predictions and also to manipulate elements
in the flowcharts.
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Urinary
System
Anatomy Review.
This topic shows the organs of the urinary system,
and the external and internal anatomy of the kidney,
including its blood supply. The nephron is covered,
including the tubular segments and the associated
blood vessels. In the renal corpuscle section, a
glomerular capillary is expanded to show the layers
of the filtration membrane, with photomicrographs
for comparison and an animation of filtration of the
membrane. Finally, the key features of the cells of
each tubular segment are presented. The quizzes
cover the structures presented.
Glomerular
Filtration. This topic presents an overview of
filtration, reabsorption, and secretion. Students
can analyze filtrate and then answer a clinical
question. Next, forces affecting filtration are
shown and the glomerular filtration rate (GFR) is
introduced. An interactive animation introduces the
discussion of autoregulation mechanisms of the GFR.
The website demonstrates sympathetic control in
emergency situations. Quizzes allow students to
answer questions on concepts covered.
Early Filtrate
Processing. This topic covers reabsorption and
secretion. It starts with an analogy for
reabsorption, and presents animations. Then it moves
through the tubular segments, presenting animations
of the movement of molecules through the luminal and
basolateral membranes of each, differentiating
between diffusion, primary active transport, and
secondary active transport throughout. Then it shows
how the countercurrent multiplier mechanism produces
the medullary osmotic gradient. The extensive quiz
questions include tubular permeability, predicting
the effects of a diuretic drug, and a game called
membrane transport trivia that can be played by two
students.
Late Filtrate
Processing. This topic covers reabsorption and
secretion from the late DCT to the medullary
collecting duct. First presented are the effects of
aldosterone and antidiuretic hormone on filtrate
processing in the late DCT and cortical collecting
duct. The medullary osmotic gradient is reviewed,
followed by changes in filtrate osmolarity as it
moves through the gradient, leading to the
discussion of final urine concentration. Finally,
final urine volume is covered. Quizzes ask students
to answer questions on the activities of various
tubular regions, predict the effects of dehydration,
and let students analyze various urine samples.
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SYSTEM
REQUIREMENTS:
MACINTOSH
233 MHz PowerPC
OS 8.6 or higher
32 MB RAM available
800 x 600 screen resolution, thousands of colors
Internet Explorer: 5.0 or higher (for online use
only), Shockwave Player 8, Flash Player 6, Quicktime
4
4x CD-ROM drive (CD-ROM)
Internet connection with 56K modem (for website)
WINDOWS
266 MHz Pentium processor
Windows 98, NT 4, 2000, or XP
64 MB RAM installed
800 x 600 screen resolution, thousands of colors
Internet Explorer: 5.0 or higher (for online use
only), Shockwave Player 8, Flash Player 6, Quicktime
4
4x CD-ROM drive (CD-ROM)
Internet connection with 56K modem (for website)
Institutional
multi-user license edition available.
Please call 800-745-4557 for discount pricing.
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