Accreditation Statement
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the University of Colorado School of Medicine and Challenger Corporation.

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Certification Statement
The University of Colorado School of Medicine designates this educational activity for a maximum of 8.0 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits he/she actually spent in the activity.

Disclosure Policy
It is the intent of University of Colorado School of Medicine to assure that its educational mission, and continuing medical education activities in particular, should not be influenced by the special interests of individuals associated with its programs. Having an interest in or an affiliation with any corporate organization does not necessarily influence a faculty's presentation, but the relationship must be made known to the program audience in accordance with the ACCME Standards for Commercial Support of Continuing Medical Education.

Activity Dates
Date of Original Release: July 15, 2003
Most Recent CME Review/Update: July 15, 2005
Edition Release Date: July 15, 2005
Expiration Date: January 15, 2010

This course will be reviewed within three years of last review date.

Copyright Statement
Challenger Gastroenterology/CC. Copyright © 2003 by Challenger Corporation. All rights reserved.

Clinical Reviewer:
Michael K. Rees, MD, MPH
Instructor of Medicine
Harvard University School of Medicine
Boston, MA

Clinical Reviewer has nothing to disclose with regard to financial support. Clinical Reviewer does not plan to discuss unlabeled/investigational uses of a commercial product.

Authors:
Viral Hepatitis
Raymond S. Koff, MD
Director of Clincal Research, The Liver Center
University of Massachusetts Memorial Health Care
UMass Memorial Medical Center
Professor of Medicine
University of Massachusetts Medical School
Boston, MA

Speaker has the following disclosures: GR: Roche, Schering, Glaxo Smith Kline, Triangle, Ortho C: Glaxo Smith Kline, Roche SB: Roche, Glaxo Smith Kline, Ortho Speaker indicates that he does not plan to discuss unlabeled/investigational uses of a commercial product.

Inflammatory Bowel Disease
Mark Peppercorn, MD
Co-Director, Inflammatory Bowel Disease Center
Beth Israel Deaconess Medical Center
Boston, MA

Speaker has the following disclosures: C: Centocor, Seliz, Proctor & Gamble, Astra Zeneca, Solvay Speaker indicates that he does not plan to discuss unlabeled/investigational uses of a commercial product.

GERD - The Next Endoscopic Frontier
Douglas Pleskow, MD
Co-Director of Endoscopy
Beth Israel Deaconess Medical Center
Assistant Professor of Medicine
Harvard Medical School
Boston, MA

Speaker has nothing to disclose with regard to financial support. Speaker indicates that he does not plan to discuss unlabeled/investigational uses of a commercial product.

Treatment Options in the Management of NSAID-Induced GI Disorders
David L. Lichtenstein, MD
Director of Endoscopy
Boston Medical Center
Associate Professor of Medicine
Boston University School of Medicine
Boston, MA

Speaker has the following disclosures: SB: TAP Pharmaceutical, Abbott Laboratories, Astra. Speaker indicates that he does not plan to discuss unlabeled/investigational uses of a commercial product.

Disclosure Key:
GR - Grant Research
C - Consultant
SB - Speakers Bureau

Target Audience:
Challenger Core Curriculum: Gastroenterology is intended for all physicians, both primary care providers and specialists, who require information on gastroenterology practices.

This course emphasizes current best practices. Participants also have access to an editorial summary to reinforce and enhance the learning experience.

Educational Need:
In these days of fast paced clinical changes it is crucial for primary care practitioners to continuously update their knowledge and skills. A wide range of topics pertinent to office practice are reviewed by the Core Curriculum in Adult Primary Care series, including all of the subspecialties in medicine and surgery.

Educational Objectives:
The educational objectives of Challenger Core Curriculum: Gastroenterology are as follows. On completing the program, the medical practitioner will be able to:

1. Describe how to utilize serological tests to identify the discrete forms of viral hepatitis - both acute and chronic
    
2. List the indications for liver biopsy
    
3. Discuss the current status of anti-viral therapy
    
4. Describe how to utilize history, physical examination, laboratory, radiology and endoscopy to diagnose ulcerative colitis, Crohn's disease and microscopic colitis
    
5. Discuss current understanding of the etiology of ulcerative colitis, Crohn's disease and microscopic colitis
    
6. List the recommended first line therapies and discuss recently introduced biological therapies
    
7. Identify which patients require intensive cancer surveillance
    
8. Describe how to utilize history, laboratory, pH monitoring and endoscopy to diagnose esophageal reflux disease
    
9. Discuss current understanding of the role of acid reflux in the etiology of Barrett esophagus and esophageal cancer
    
10. List the recommended intensity and duration of acid suppression and/or motility therapies
     
11. Identify those candidate(s) for surgical repair utilizing either laparoscopic or endoscopic technique
     
12. Discuss the GI toxicity of commonly used over the counter and prescription NSAIDS in the absence or presence of ASA
     
13. Describe the profile of patients most at risk of developing GI toxicity
     
14. Discuss the mechanism by which H2-blockers, PPI's and prostaglandins prevent GI toxicity
     
15. Describe how to choose between selective vs. non-selective NSAIDs and whether or not a cytoprotective agent is required