Program Objectives     Topics Covered       Pricing

You won't have to spend years in school to understand the concepts offered in Genetic Engineering. In this program, you'll see that organisms have a remarkable ability to manipulate DNA and transfer genes between organisms, keeping certain traits and dropping others.

A graphic, step-by-step examination of the procedures involved in transferring a human insulin gene to bacteria illustrate the techniques and processes of gene manipulation and transfer. With Genetic Engineering, you'll see genetic changes occurring from the cellular point of view.

Topics covered in this program include: DNA Composition and Its Function as Genetic Material; The Use of Natural Variation in Genes for Selective Breeding; Changes in Genes Through Mutation; A Step By Step Guide Through the Experimental Process of Genetic Engineering; Examples of modern Genetic Engineering in Microbes, Plants, and Animals; and the Applications of Genetic Engineering in Medicine and Gene Therapy.

Presentation
The Presentation portion of this program includes audio-narrated scenes featuring the content from the objectives.





Interactive Lessons
Students can work through different activities that directly reinforce the information learned in the Presentation.

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Program Objectives

I. Introduction

II. DNA

A. DNA and Chromosomes

B. DNA composition

1. Nucleotides and base pairing

2. All DNA is comprised of the same four nucleotides

3. Genes are codes for proteins

a. Types of proteins

C. From DNA to protein

III. Gene Variation

A. Selective breeding -- using variations of nature

B. Mutations -- creating new variations

C. Modern applications

1. Controlling inheritance of altered traits

IV. Genetic Engineering

A. Overview of the basic steps in genetic engineering

B. Diabetes and the need for insulin

C. A method for producing human insulin in bacteria

1. Isolating and cutting DNA

a. Restriction enzymes

2. Cloning DNA

3. Vectors

a. Viruses as vectors

b. Plasmids as vectors

4. Making recombinant DNA

5. Transformation

a. Identifying transformed bacteria

b. The gene library

c. The shotgun approach

6. Probing the gene library to identify colonies with the desired gene - DNA & RNA probes

a. Identifying the bound probes

b. Antibody probes

7. Mass production of the gene product

8. Expressing eukaryotic genes

V. Examples of Modern Genetic Engineering

A. Genetic engineering in microbes

1. Human growth hormone production in bacteria

2. Bovine growth hormone

3. Waterproof glue

4. Cheese from microbes

B. Genetic engineering in plants

1. Methods for transferring DNA through the cell wall

a. The Ti plasmid as a vector

2. Bacillus thuringiensis insecticide

a. Transfer of the insecticidal gene to crop plants

3. Longer lasting tomatoes

4. Frost protection in strawberry plants

5. Nitrogen fixation

C. Genetic engineering in animals

1. Animals that produce products for humans

2. Animal cloning

a. Dolly - the clone of an adult sheep

D. Genetic engineering in health care

1. Traditional vaccines

2. Genetically engineered vaccines

a. Vaccinating with viruses

b. DNA vaccines

E. Genetic engineering in humans

1. Gene therapy

a. Treatment of cystic fibrosis

b. Research toward treatment of other diseases

VI. Conclusion

		Designed with these features, or to meet the needs of the listed grade levels.

		Contains some of the listed features, or should be appropriate depending on students skill level.

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Pricing

Hybrid CD-ROM
SingleUser, 1 $99.95
Order #: X0991139HY

Hybrid CD-ROM
LabPack, 5 $240.00
Order #: X0991139HYL5

Hybrid CD-ROM
LabPack, 10 $420.00
Order #: X0991139HYLX

Please call 1-800-745-4557 to Specify Windows or Mac

Specify Windows or Mac Network, 10 $240.00
Order #: X0991139HYNX

Specify Windows or Mac Network, 30 $540.00
Order #: X0991139HYNZ

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